Nebido 1000 mg 4 ml solution for injection Patient Information Leaflet PIL emc 14631

These symptoms can occur during or immediately after injection and are reversible. Testosterone and derivatives have been reported to increase the activity of coumarin derived oral anti-coagulants.-Patients receiving oral anti-coagulantsrequire close monitoring, especially at the beginning or end of androgen therapy. Increased monitoring of the prothrombin time, and INR determinations, are recommended. The truth is, this is a substance that is really intended and primarily used by those in therapeutic settings. Because it is a low ester form of testosterone, the truth is, it could be theoretically used as a performance enhancer. But because of the longer ester chain, this means that it will be absorbed and noticed a lot slower than other forms of testosterone, namely testosterone cypionate or testosterone enanthate.

• It has an active half-life of approximately days, requiring injections every 8-12 weeks.
• In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.
• Depending on serum testosterone levels and clinical symptoms, the first injection interval may be reduced to a minimum of 6 weeks as compared to the recommended range of 10 to 14 weeks for maintenance.
• Following intramuscular injection of testosterone undecanoate as an oily solution, the compound is gradually released from the depot and is almost completely cleaved by serum esterases into testosterone and undecanoic acid.
• The undecanoic acid is metabolised by B-oxidation in the same way as other aliphatic carboxylic acids.
• Your doctor may give you the second injection after only six weeks in order to quickly reach the necessary testosterone level.

NEBIDO 1000MG/4ML SOLUTION FOR INJECTION

Injections with this frequency are capable of maintaining sufficient testosterone levels and do not lead to accumulation..Serum testosterone levels should be measured before start and during initiation of treatment. Depending on serum testosterone levels and clinical symptoms, the first injection interval may be reduced to a minimum of 6 weeks as compared to the recommended range of 10 to 14 weeks for maintenance. With this loading dose, sufficient steady state testosterone levels may be achieved more rapidly. Nebido Injection is a product that contains Testosterone undecanoate, a male hormone, as the active ingredient. It is injected into a muscle in your body, where it can be stored and gradually released over a period of time.

Because of its ester makeup, it has one of the longest half-lives in existence as far as androgenic compounds go. This means that if you’re expecting the compound to be out of your system, for example, a concern of many athletes using a similar compound, you have to be fully aware that this is going to be in your system for a longer duration. The active half-life duration of Nebido is over three months, whereas other ester chains like test cypionate or test enanthate only have half-lives of around a week. This should emphasize in very big letters just how slow-acting Nebido can be, so again, if you want something that packs a punch in a quick time period, this is absolutely not the compound to use.

GEBRAUCHSINFORMATION: INFORMATION FÜR DEN ANWENDER Nebido® 1000 mg Injektionslösung

Measurements should be performed at the end of an injection intervaland clinical symptoms considered. Serum levels below normal range would indicate the need for a shorter injection interval. In case of high serum levels an extension of the injection interval may be considered. Careful monitoring of serum testosterone levels is required during maintenance of treatment.

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Contact your medical professional immediately to learn if it is still safe for you to be taking Nebido injections and whether you can still benefit from it. Additionally, Nebido injections are not intended for use in women and they are not intended for use in children or adolescents. There is no benefit in using Nebido injections for males under the age of 18. All of these people that fit within these descriptions should not use Nebido injections as a treatment for any condition.

Nebido is an intramuscularly administered depot preparation of testosterone undecanoate and thus circumvents the first-pass effect. Following intramuscular injection of testosterone undecanoate as an oily solution, the compound is gradually released from the depot and is almost completely cleaved by serum esterases into testosterone and undecanoic acid. An increase in serum levels of testosterone above basal values may be seen one day after administration.

•    hypersensitivity to the active substance or to any of the excipients. It is widely regarded as an invaluable reference source by healthcare professionals, the National Medicines Information Centre and the Department of Health. Please be sure to inform your doctor if you suffer from a disturbance of blood clotting, because this is important for your doctor to know before deciding to inject Testosterone Undecanoate. There is no data available on the use of Testosterone Undecanoate in males under 18 years of age. Always take this medicine exactly as Dianabol 10 mg P&B Labs buy online your doctor or pharmacist has told you.